HEALTH- RELATED QUALITY OF L IFE IN EARLY BREAST CANCER PATIENTS WITH HORMON E RESPONSIVE
By: Rukminingsih, Fef.
Contributor(s): Andayani, Tri Murti.
Publisher: M P Innovare Academic Sciences Pvt Ltd 2018Edition: Vol.10(12).Description: 47-49p.Subject(s): PHARMACEUTICSOnline resources: Click here In: International journal of pharmacy and pharmaceutical scienceSummary: Objective : The management of early breast cancer (EBC) is performed with a series of treatments consisting of surgery and systemic therapy, along with long -term endocrine therapy for hormone responsive. The treatment generates a high illness effect that will affect the life quality of EBC patients. Th e objective of this study was to measure EBC patients ’ quality of life after undergo ing the treatment. Method s: A cross -sectional study was conducted by interviewing EBC patients using EQ -5D -5L instrument at private hospital s in Yogyakarta and Semarang , Indonesia . The EBC patients were women aged 18 -60 y who ha d undergone surgery in 2010 -2013 and receive d endocrine ther apy. Result s : Of the 71 patients identified , 45 patients were in disease -free survival (DFS) state , 8 patients were in locoregional recurrence (LR), and 18 patients were in metastasis (M) state . Mobil ity and self -care problems occurred in patients who had metastasis (4. 23%). The p roblem of usual activities occur ed in patients who had recurrence (22. 54%). Most of the patients (84.51%) had pain problem , and all patients had an anxiety problem. The mean utility score (SD) in DFS patient s was 0.841 (0.052) , in LR patients w as 0.758 (0.092) , and in patients who had metastasis was 0. 653 (0.104). The mean scores of EQ -5D VAS (SD) for EBC patients in DFS, LR and M health state were 86.56 (6.29), 81.88 (5.30), and 69.17 (5.75), respectively. Concl usio n : The health states of EBC significantly affect HRQOL of patients . Efforts should be made to improve the quality of life of EBC patie nts especially in terms of pain and anxiety reduction.Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
---|---|---|---|---|---|---|
Articles Abstract Database | School of Pharmacy Archieval Section | Not for loan | 2020955 |
Objective
:
The management of early breast cancer (EBC) is performed with a series of treatments consisting of
surgery and systemic therapy, along
with long
-term endocrine therapy for hormone responsive.
The treatment generates
a high illness effect that will affect the
life
quality of EBC
patients.
Th
e objective of this study
was
to measure EBC patients
’ quality of life
after
undergo
ing
the
treatment.
Method
s: A cross
-sectional study was conducted by interviewing EBC patients using
EQ
-5D
-5L
instrument
at
private hospital
s in
Yogyakarta
and
Semarang
, Indonesia
. The EBC patients were women aged 18
-60 y
who ha
d undergone surgery in 2010
-2013 and receive
d endocrine ther
apy.
Result
s
:
Of the 71 patients identified
, 45 patients were in disease
-free
survival (DFS)
state
, 8 patients were in locoregional recurrence (LR), and 18
patients
were
in metastasis
(M)
state
. Mobil
ity and self
-care problems occurred in
patients
who had
metastasis (4.
23%).
The p
roblem of
usual activities
occur
ed
in patients who had
recurrence
(22.
54%). Most of
the
patients (84.51%) had pain
problem
, and
all patients had an
anxiety
problem. The mean
utility score (SD)
in DFS patient
s was
0.841
(0.052)
, in LR patients w
as
0.758
(0.092)
, and in patients who had metastasis was 0.
653
(0.104).
The mean
scores
of EQ
-5D VAS (SD) for EBC patients in DFS, LR and M health state
were 86.56
(6.29), 81.88 (5.30),
and
69.17 (5.75), respectively.
Concl
usio
n
:
The
health states of EBC significantly affect HRQOL
of
patients
. Efforts should be made to improve the quality of life of EBC patie
nts
especially in terms of pain
and anxiety reduction.
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